Metabolism US Medical PG Flashcards - Medical Study Cards
Master Metabolism with OnCourse flashcards. These spaced repetition flashcards are designed for medical students preparing for NEET PG, USMLE Step 1, USMLE Step 2, MBBS exams, and other medical licensing examinations.
Metabolism Flashcard Deck - 10 Cards
Flashcard 351: Pyruvate dehydrogenase is regulated via positive feedback by _____, Ca2+, and increased NAD+/NADH ratio
Answer: ADP
Extra:
Watch Pyruvate Dehydrogenase Complex [https://dashboard.sketchy.com/study/medical/courses/medical-biochemistry/units/medical-biochemistry-metabolism/videos/medical-biochemistry-metabolism-carbohydrates-pyruvate-dehydrogenase-complex?utm_source=anki&utm_medium=partnership&utm_campaign=february_update&utm_content=medical]
https://onlinemeded.org/spa/metabolism/pyruvate-dehydrogenase/acquire?ref=anki
Flashcard 352: What mitochondrial enzyme reduces superoxide (O2-) to H2O2?
_____
Answer: Superoxide dismutase
Extra:
https://onlinemeded.org/spa/infectious-disease?ref=anki
Flashcard 353: Effect of diabetes on hepatic glycolysis: _____ deficiency
- No PFK-2 activity due to lack of insulin
- No glucose trapping in liver leads to elevated blood glucose (hyperglycemia)
Answer: Glucokinase
Extra: In diabetes mellitus, insulin levels are low. Insulin normally induces the transcription of glucokinase; therefore, glucokinase is deficient in diabetes. This prevents the liver from effectively 'trapping' glucose (converting it to glucose-6-phosphate), which contributes to postprandial hyperglycemia.
https://onlinemeded.org/spa/metabolism
Flashcard 354: What vitamin is derived from the amino acid tryptophan?
_____
Answer: Vitamin B3 (niacin)
Extra:
Watch Amino Acid Derivatives [https://dashboard.sketchy.com/study/medical/courses/medical-biochemistry/units/medical-biochemistry-metabolism/videos/medical-biochemistry-metabolism-amino-acids-and-proteins-amino-acid-derivatives?utm_source=anki&utm_medium=partnership&utm_campaign=february_update&utm_content=medical]Watch associated Bootcamp video [https://app.bootcamp.com/med-school/gastroenterology/videos/physiology?index=16]
https://onlinemeded.org/spa/dna-to-protein/amino-acids/acquire?ref=anki
Flashcard 355: _____ may be converted to H2O via the enzyme glutathione peroxidase
Answer: H2O2
Extra:
https://onlinemeded.org/spa/metabolism?ref=anki
Flashcard 356: An enteropeptidase deficiency will lead to diarrhea, failure to thrive, and edema (due to _____)
Answer: hypoproteinemia
Extra:
https://onlinemeded.org?ref=anki
Flashcard 357: Fructose is extruded from the intestinal cell into the blood by _____
Answer: GLUT-2 (facilitated diffusion)
Extra:
https://onlinemeded.org/spa/metabolism?ref=anki
Flashcard 358: What is the mode of inheritance of hereditary hyperbilirubinemias (e.g. Gilbert, Crigler-Najjar, Dubin-Johnson)?
_____
Answer: Autosomal recessive
Extra:
Watch Autosomal Recessive Diseases [https://dashboard.sketchy.com/study/medical/courses/medical-biochemistry/units/medical-biochemistry-clinical-genetics/videos/medical-biochemistry-clinical-genetics-autosomal-recessive-diseases-autosomal-recessive-diseases?utm_source=anki&utm_medium=partnership&utm_campaign=february_update&utm_content=medical]
Watch Lab Evaluation of Liver Injury & Hyperbilirubinemia [https://dashboard.sketchy.com/study/medical/courses/medical-pathophysiology/units/medical-pediatrics-hepatobiliary/videos/medical-pathophysiology-hepatobiliary-gallbladder-and-biliary-tract-disease-lab-evaluation-of-liver-injury-and-hyperbilirubinemia?utm_source=anki&utm_medium=partnership&utm_campaign=february_update&utm_content=medical]Watch associated Bootcamp video [https://app.bootcamp.com/med-school/gastroenterology/videos/pancreatic-and-biliary-pathology?index=9]
https://onlinemeded.org/spa/gastroenterology/jaundice/acquire?ref=anki
Flashcard 359: In the _____, ethanol may be converted to acetaldehyde via the enzyme catalase
Answer: peroxisome
Extra:
Watch Alcohol Metabolism [https://dashboard.sketchy.com/study/medical/courses/medical-biochemistry/units/medical-biochemistry-metabolism/videos/medical-biochemistry-metabolism-alcohol-metabolism-alcohol-metabolism?utm_source=anki&utm_medium=partnership&utm_campaign=february_update&utm_content=medical]
https://onlinemeded.org/spa/metabolism?ref=anki
Flashcard 360: Glucose-6-phosphate dehydrogenase (G6PD) deficiency is a disorder resulting in reduced _____ of G6PD
Answer: half-life
Extra:
Watch associated Bootcamp video [https://app.bootcamp.com/med-school/hematology-and-oncology/videos/normocytic-anemia?index=7]
https://onlinemeded.org/spa/metabolism?ref=anki
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