Metabolism US Medical PG Flashcards - Medical Study Cards
Master Metabolism with OnCourse flashcards. These spaced repetition flashcards are designed for medical students preparing for NEET PG, USMLE Step 1, USMLE Step 2, MBBS exams, and other medical licensing examinations.
Metabolism Flashcard Deck - 10 Cards
Flashcard 341: After adipose stores have been depleted (prolonged starvation), vital _____ degradation accelerates, leading to organ failure and death
Answer: protein
Extra:
https://onlinemeded.org/spa/metabolism?ref=anki
Flashcard 342: What non-volatile acid may be elevated with ethylene glycol ingestion?
_____
Answer: Oxalic acid
Extra:
Watch Acid/Base Disorders [https://dashboard.sketchy.com/study/medical/courses/medical-pathophysiology/units/medical-pathophysiology-renal/videos/medical-pathophysiology-renal-volume-electrolyte-and-acidbase-disorders-acidbase-disorders?utm_source=anki&utm_medium=partnership&utm_campaign=february_update&utm_content=medical]Watch associated Bootcamp video [https://app.bootcamp.com/med-school/nephrology/videos/acid-base-physiology?index=6]
https://onlinemeded.org/spa/renal?ref=anki
Flashcard 343: Where in the cell does conversion of alcohol -> acetaldehyde take place?
_____
Answer: Cytosol
Extra:
Watch Alcohol Metabolism [https://dashboard.sketchy.com/study/medical/courses/medical-biochemistry/units/medical-biochemistry-metabolism/videos/medical-biochemistry-metabolism-alcohol-metabolism-alcohol-metabolism?utm_source=anki&utm_medium=partnership&utm_campaign=february_update&utm_content=medical]
https://onlinemeded.org/spa/metabolism?ref=anki
Flashcard 344: In total, the TCA cycle produces _____ NADH per acetyl-CoA
Answer: 3
Extra:
Watch Citric Acid Cycle (TCA) [https://dashboard.sketchy.com/study/medical/courses/medical-biochemistry/units/medical-biochemistry-metabolism/videos/medical-biochemistry-metabolism-carbohydrates-tca-cycle?utm_source=anki&utm_medium=partnership&utm_campaign=february_update&utm_content=medical]
https://onlinemeded.org/spa/metabolism?ref=anki
Other:
Flashcard 345: Wilson disease results in lack of copper transport into _____ and lack of incorporation into ceruloplasmin
Answer: bile
Extra:
Watch associated Bootcamp video [https://app.bootcamp.com/med-school/gastroenterology/videos/hepatic-pathology?index=18]
https://onlinemeded.org?ref=anki
Atlas:
Flashcard 346: Homogentisic acid (from tyrosine) may be converted to _____ via the enzyme homogentisate oxidase
Answer: maleylacetoacetate
Extra:
https://onlinemeded.org/spa/dna-to-protein/amino-acids/acquire?ref=anki
Flashcard 347: What form of hemoglobin protects against sickling in sickle cell anemia?
_____
Answer: HbF
Extra:
Watch Sickle Cell Disease [https://dashboard.sketchy.com/study/medical/courses/medical-pathophysiology/units/medical-pathophysiology-blood-coagulation/videos/medical-pathophysiology-blood-and-coagulation-normocytic-and-macrocytic-anemias-sickle-cell-disease?utm_source=anki&utm_medium=partnership&utm_campaign=february_update&utm_content=medical]Watch associated Bootcamp video [https://app.bootcamp.com/med-school/hematology-and-oncology/videos/normocytic-anemia?index=4]
https://onlinemeded.org/spa/pediatrics/sickle-cell-disease/acquire?ref=anki
Other:
Flashcard 348: ATP synthase inhibitors cause a(n) _____ proton gradient and a block of ATP synthesis
Answer: increased
Extra:
Watch Electron Transport Chain (ETC)/Oxidative Phosphorylation [https://dashboard.sketchy.com/study/medical/courses/medical-biochemistry/units/medical-biochemistry-metabolism/videos/medical-biochemistry-metabolism-carbohydrates-electron-transport-chainoxidative-phosphorylation?utm_source=anki&utm_medium=partnership&utm_campaign=february_update&utm_content=medical]
https://onlinemeded.org/spa/metabolism/electron-transport-chain/acquire?ref=anki
Flashcard 349: Pyruvate dehydrogenase is regulated via positive feedback by _____, Ca2+, and increased NAD+/NADH ratio
Answer: ADP
Extra:
Watch Pyruvate Dehydrogenase Complex [https://dashboard.sketchy.com/study/medical/courses/medical-biochemistry/units/medical-biochemistry-metabolism/videos/medical-biochemistry-metabolism-carbohydrates-pyruvate-dehydrogenase-complex?utm_source=anki&utm_medium=partnership&utm_campaign=february_update&utm_content=medical]
https://onlinemeded.org/spa/metabolism/pyruvate-dehydrogenase/acquire?ref=anki
Flashcard 350: Effect of diabetes on hepatic glycolysis: _____ deficiency
- No PFK-2 activity due to lack of insulin
- No glucose trapping in liver leads to elevated blood glucose (hyperglycemia)
Answer: Glucokinase
Extra: In diabetes mellitus, insulin levels are low. Insulin normally induces the transcription of glucokinase; therefore, glucokinase is deficient in diabetes. This prevents the liver from effectively 'trapping' glucose (converting it to glucose-6-phosphate), which contributes to postprandial hyperglycemia.
https://onlinemeded.org/spa/metabolism
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