Metabolism — Flashcards

Flashcard 1341: Glycogen phosphorylase is stimulated by _____ in the liver

Answer: glucagon

Flashcard 1342: Fetal hemoglobin (HbF) has a much _____ binding affinity for O2 than adult hemoglobin (HbA)

Answer: higher

Flashcard 1343: If methylmalonyl-CoA mutase is dysfunctional, _____ accumulates in the blood and urine

Answer: methylmalonic acid

Flashcard 1344: What is the mode of inheritance of protein C or S deficiency?_____

Answer: Autosomal dominant

Flashcard 1345: Picking of the skin or biting of the lips due to hyperuricemia is seen in _____ syndrome

Answer: Lesch-Nyhan

Flashcard 1346: Homocystinuria can be caused by _____ deficiencies.

Answer: vitamin (B6, B9, or B12)

Extra: Classic homocystinuria is most commonly caused by an autosomal recessive deficiency of cystathionine beta-synthase (CBS). However, elevated homocysteine (and subsequent homocystinuria) can also be caused by deficiencies in B6 (pyridoxine), B9 (folate), or B12 (cobalamin).

Flashcard 1347: _____ is the enzyme responsible for oxidation and organification of iodide.

Answer: Thyroid peroxidase

Flashcard 1348: Which lysosomal storage diseases (2) have an X-linked recessive inheritance? _____

Answer: Fabry disease, Hunter syndrome

Flashcard 1349: Does the Cahill cycle result in regeneration of NAD+? _____

Answer: No

Flashcard 1350: What does the carrier molecule biotin carry in its activated form? _____

Answer: CO2