Lipid metabolism — Flashcards

Hypothyroidism may contribute to development of _____ due to dyslipidemia and endothelial dysfunction

Progesterone may be converted to _____ via the enzyme 17α-hydroxylase

In adipose tissue, triglycerides are broken down into glycerol and fatty acids by the enzyme _____

Type IIa familial dyslipidemia is due to either: - absent or defective _____ - defective Apo B-100

Niacin (Vitamin B3) _____ decreases serum triglycerides by decreasing hepatic _____ secretion

The triglycerides inside the chylomicron are broken down into _____ by lipoprotein lipase in the vicinity of the adipocytes (or peripheral tissue)

Increased levels of cholesterol inside the hepatocyte leads to decreased activity of the enzyme _____

Acetyl-CoA is converted to _____ via the enzyme acetyl-CoA carboxylase (fatty acid synthesis)

Which lysosomal storage disease may be treated with recombinant enzyme therapy? _____

Once in the vicinity of adipocytes, apoprotein _____ on the chylomicron activates the enzyme lipoprotein lipase (LPL)