Gastroenterology & Hepatology — Flashcards

Flashcard 621: Smoking results in: _____ risk for Crohn disease ↓ risk for Ulcerative colitis

Answer: ↑

Flashcard 622: The cause of Crohn's disease is unknown, but there is a strong _____

Answer: genetic susceptibility

Flashcard 623: Crohn's disease is more susceptible to strictures, fistulas, & adhesions because _____

Answer: of transmural inflammation → more complete loss of bowel wall integrity

Flashcard 624: _____ is an extraintestinal manifestation seen in both UC and Crohn's, but extraintestinal manifestations (EIMs) are generally more common in Crohn's disease

Answer: Uveitis

Extra: Most extraintestinal manifestations (Uveitis, Erythema Nodosum, Peripheral Arthritis) are more common in Crohn's Disease than in Ulcerative Colitis. The notable exception is **Primary Sclerosing Cholangitis (PSC)**, which has a very strong association with **Ulcerative Colitis** (about 70-80% of PSC patients have UC).

Flashcard 625: Investigation of choice to confirm the diagnosis of _____ is Endoscopy with biopsy.

Answer: Crohn's disease

Flashcard 626: _____ is the blockage of the small intestine that impedes passage of intestinal contents

Answer: Small bowel obstruction

Flashcard 627: What is the final-line surgical management for haemorrhoids? _____ or haemorrhoidal artery ligation

Answer: Haemorrhoidectomy

Flashcard 628: What is the surgical management of ulcerative colitis? _____

Answer: Total proctocolectomy

Flashcard 629: Ulcerative colitis is typically characterised by _____ lower quadrant pain

Answer: left

Flashcard 630: _____ on a blood test correlates well with disease activity of Crohn's

Answer: CRP