Gastroenterology & Hepatology — Flashcards

Flashcard 501: Hepatitis B serology: _____ is positive when there is previous or current infection

Answer: Hepatitis B core antibody (anti-HBc)

Flashcard 502: Those at high risk of Hepatitis A (e.g. close contact) can be offered a _____

Answer: vaccination

Flashcard 503: _____ is a self-limiting infection with hepatitis A virus that causes inflammation of the liver

Answer: Hepatitis A

Flashcard 504: Hepatitis A symptoms often improve once _____ occurs

Answer: jaundice

Flashcard 505: Approximately _____% of infants born to HBeAg positive mothers will develop chronic hepatitis B if no immunoprophylaxis is given.

Answer: 90

Extra: Chronic Hepatitis B infection risk by age of acquisition: - Neonates (vertical transmission): ~90% risk of chronicity. - Children (1-5 years): 30-50% risk. - Adults: <5-10% risk (most adults clear the virus successfully).

Flashcard 506: Hepatitis B serology: _____ is positive when there is current infection (acute or chronic)

Answer: Hepatitis B surface antigen (HBsAg)

Flashcard 507: LFTs for hepatitis A will show: _____ ALT & AST Normal or ↑ bilirubin Normal or ↑ PT

Answer: Significantly ↑

Flashcard 508: Hepatitis A presents with _____ pain

Answer: RUQ

Flashcard 509: Hepatitis B serology: HbsAg _____ Anti-HBs +ve Anti-HBc +ve = previous infection

Answer: -ve

Flashcard 510: There are 3 main types of hepatitis B; _____ & Fulminant, Chronic

Answer: Acute