Gastroenterology & Hepatology UK Medical PG Flashcards - Medical Study Cards
Master Gastroenterology & Hepatology with OnCourse flashcards. These spaced repetition flashcards are designed for medical students preparing for NEET PG, USMLE Step 1, USMLE Step 2, MBBS exams, and other medical licensing examinations.
Gastroenterology & Hepatology Flashcard Deck - 10 Cards
Flashcard 511: What investigatory result helps distinguish between alcoholic hepatitis and viral hepatitis?
Answer: AST:ALT ratio.
- **Alcoholic hepatitis**: Ratio > 2:1 (AST is usually <300-500 IU/L).
- **Viral hepatitis**: Ratio ~ 1:1 (Both AST and ALT are markedly elevated, often >1000 IU/L, with ALT > AST).
Flashcard 512: Hepatitis A serology with +ve HAV-IgM & +ve HAV-IgG indicates _____
Answer: acute hepatitis A infection
Flashcard 513: What is the most important lifestyle advice for a patient with hepatitis regarding substance use?
Answer:
Extra: Avoidance of alcohol is crucial in patients with hepatitis as it accelerates liver damage, promotes progression to cirrhosis, and can trigger acute-on-chronic liver failure.
Flashcard 514:
Hepatitis A usually lasts < _____
Answer: 3 months
Flashcard 515: Hepatitis B serology:
HbsAg _____
Anti-HBs -ve
Anti-HBc IgM +ve
= Acute Hepatitis B
Answer: +ve
Flashcard 516: What are the primary serologic tests for Hepatitis A diagnosis?
Acute infection = _____
Past infection/Immunity = Anti-HAV IgG
Answer: Anti-HAV IgM
Extra: Hepatitis A is a self-limiting viral infection transmitted via the fecal-oral route. Serology is the primary method of diagnosis:
- **Anti-HAV IgM**: Detectable at the onset of symptoms, peaks early, and disappears within 3-6 months. Indicates **acute infection**.
- **Anti-HAV IgG**: Appears shortly after IgM and persists for life, providing immunity. Indicates **past infection or vaccination**.
- **HAV RNA (PCR)**: Can detect the virus in blood/stool before IgM appears, but is not standard clinical practice.
Flashcard 517:
Hepatitis A resolution phase lasts up to _____ & can presents with malaise & hepatic tenderness
Answer: 6 months
Flashcard 518:
If a case of hepatitis B is suspected then _____
Answer: notify public health
Flashcard 519: Hepatitis A serology with -ve HAV-IgM & +ve HAV-IgG indicates _____ or immunity
Answer: past hepatitis A infection
Flashcard 520: Hepatitis A incubation period is ~ _____
Answer: 28 days
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