Clinical Pharmacology and Drug Toxicity — Flashcards

Chronic use of interferon alpha is associated with patients experiencing flu-like symptoms; as well as _____, neutropenia, and myopathy

_____ is used in the treatment of MaroteauxLamy syndrome.

Signs and symptoms of Strychnine poisoning: CRAMPingC_____Reflexes increasedAwful tasteMind is conciousPupils dilated

_____, which chelates both iron and aluminum, acts as a siderophore for the species Rhizopus, enhancing its growth and pathogenicity. This leads to an increased risk for Mucormycosis.

Vitamin _____ excess is characterized by facial flushing; can be avoided by taking NSAIDs if given 30-60 minutes before administration

If taken during pregnancy, Methotrexate can cause _____ defects, most commonly spina bifida or anencephaly

Because RANKL is also expressed on _____ cells, a side effect of Denosumab treatment is immunosuppression

DRESS syndrome occurs _____-8 weeks after drug exposure

Electrolyte abnormalities, such as _____ and hypomagnesemia, can result from amphotericin use

Chronic vitamin _____ toxicity may cause arthralgias (joint complication)