Clinical Pharmacology and Drug Toxicity — Flashcards

_____ is used as an antidote for methanol or ethylene glycol poisoning

Valproic acid causes _____ appetite and weight gain

In addition to nephrotoxicity, cyclosporine and tacrolimus may also have _____-toxicity (especially Tacrolimus)

DOC for treatment of Type _____ tyrosinemia is Nitisinone

Adverse effects of chronic aspirin use include:- _____ injury- acute interstitial nephritis- GI bleeding

Vancomycin is known to be both _____-toxic and nephro-toxic

Chronic vitamin _____ toxicity may cause pseudotumor cerebri (CNS complication)

Allopurinol is used to prevent _____ deposition in the renal tubules during tumor lysis syndrome

Adverse effects of sirolimus (rapamycin) include _____ and insulin resistance

Cyclophosphamide can cause a congenital syndrome (remember with the mnemonic conGEAL) - congenital: _____, Ear and facial abnormalities, Absence of digits, Limb hypoplasia

Hint: G