Clinical Pharmacology and Drug Toxicity — Flashcards

Which phase of clinical trials involves patients with target disease?_____

Which drug of abuse increases binding of thyroid hormone to TBG?_____

The CC/CNS dose ratio for Bupivacaine is _____

QTc interval prolongation is observed with the use of _____.

ACE inhibitors are a risk factor for type _____ renal tubular acidosis

What is the most characteristic form of dose related toxicity due to phenytoin use?_____

_____ is contraindicated in cerebrovascular accidents

_____ is a non-FDA approved drug which speeds up the metabolism of alcohol and accelerates recovery

What is the most effective anti-VEGF ligand indicated for diabetic macular edema?_____

Amiodarone causes _____ subcapsular cataract