Clinical Pharmacology and Drug Toxicity — Flashcards

Flashcard 221: _____ is acute psychotic symptoms seen after intramuscular administration of penicillin G, due to pseudoallergic/pseudoanaphylactic reaction

Answer: Hoigne Syndrome

Flashcard 222: Injecting illicit drugs into the skin intradermally or subcutaneously to achieve slower absorption and to decreased risk of overdose is known as _____

Answer: skin popping

Flashcard 223: Do Carbamates cause Intermediate syndrome?

Answer: No

Extra: Intermediate syndrome is characteristically associated with **Organophosphate** poisoning (occurring 24-96 hours after exposure). It is generally **not** seen with carbamate poisoning because carbamates are reversible inhibitors of acetylcholinesterase and have a shorter duration of action.

Flashcard 224: Is miosis a universal finding in opioid intoxication?_____

Answer: No

Flashcard 225: _____ is an anti-glaucoma drug that may result in CNS depression and apnoea in neonates.

Answer: Brimonidine

Flashcard 226: Which teratogenic drug leads to VACTERL defects?

Answer: Statins

Flashcard 227: Protease inhibitor that is associated with intracranial bleeding is _____.

Answer: tipranavir

Flashcard 228: _____ is used in the treatment of hypercalcemia due to vitamin D toxicity

Answer: Dexamethasone

Flashcard 229: Which phase of clinical trials involves real world patients?_____

Answer: Phase IV

Flashcard 230: Intoxication of _____ shows a biphasic pattern

Answer: nicotine/tobacco