Clinical Pharmacology and Drug Toxicity — Flashcards

Hydrolysis of fosphenytoin yields _____ which increases the risk of hyperphosphatemia in renal failure patients.

Adverse effects of epoprostenol and iloprost include _____ and jaw pain

In case of cyanide poisoning, there is _____ in the absence of hypoxemia (hypoxemia/hypoxia)

_____ toxicities can be remembered by the mnemonic caNNOT:NephrotoxicityNeuromuscular blockadeOtotoxicityTeratogen (deafness in neonates)

Prednisolone is given at the daily dose of _____mg/kg (max 60mg) for 6 weeks followed by an alternate dose of 1.5mg/kg (max 40mg) for the next 6-8 weeks for minimal change disease

Activated charcoal is not effective in case of poisoning with _____, corrosives, cyanide, and alcohols.

Penicillins can result in type _____ hypersensitivity reactions, mediated by IgE causing anaphylaxis

Cladribine use can result in _____-toxicity and neuro-toxicity

_____, previously known as non-cardiogenic pulmonary edema, is an uncommon complication associated with heroin overdose.

Which NNRTIs (2) are teratogenic?_____