Clinical Pharmacology and Drug Toxicity — Flashcards

Toxin requirements for Hemoperfusion:Low _____ Low endogenous clearance and bound by activated charcoal

Bleomycin can cause pulmonary fibrosis due to upregulation of _____ and IL-18 in the lungs, inducing lung inflammation

In case of cyanide poisoning, there is _____ in the absence of hypoxemia (hypoxemia/hypoxia)

_____, previously known as non-cardiogenic pulmonary edema, is an uncommon complication associated with heroin overdose.

Penicillins can result in type _____ hypersensitivity reactions, mediated by IgE causing anaphylaxis

Activated charcoal is not effective in case of poisoning with _____, corrosives, cyanide, and alcohols.

The botulinum toxin type _____ is associated with sudden death.

The dose of heparin has to be _____ in heparin resistance

_____ toxicities can be remembered by the mnemonic caNNOT:NephrotoxicityNeuromuscular blockadeOtotoxicityTeratogen (deafness in neonates)

One adverse effect associated with digoxin is _____, which is an indicator of poor prognosis