Antimicrobial Agents — Flashcards

Flashcard 471: The drug of choice for treatment of vivax malaria during pregnancy is _______.

Answer: Chloroquine

Flashcard 472: Drug of choice for plasmodium vivax is

Answer: Chloroquine

Flashcard 473: A 23-year-old female presented with burning pain during micturition. On investigations, she is found to be suffering from co-infection with Chlamydia and Gonococcus. The treatment of choice for this patient is:

Answer: Ceftriaxone + Azithromycin (or Doxycycline)

Extra: Co-infection with *Neisseria gonorrhoeae* and *Chlamydia trachomatis* requires dual therapy. \n\n1. **Ceftriaxone** (IM) for Gonococcus. \n2. **Azithromycin** (1g PO single dose) or **Doxycycline** (100mg PO BID for 7 days) for Chlamydia. \n\nNote: Recent guidelines (CDC) now prefer Doxycycline over Azithromycin for Chlamydia, but dual therapy remains the principle for co-infection.

Flashcard 474: Drug of choice for primary syphilis is :

Answer: Benzathine penicillin G

Flashcard 475: Drug of choice for acute (pneumococcal) lobar pneumonia is :

Answer: Amoxicillin

Flashcard 476: Drug of choice for chlamydial infection in pregnancy is:

Answer: Azithromycin

Flashcard 477: Drug of choice in a patient with severe complicated falciparum malaria is :

Answer: IV Artesunate

Extra: WHO and national guidelines recommend IV Artesunate as the drug of choice for severe/complicated malaria. This is followed by a full course of oral ACT (Artemisinin-based Combination Therapy) once the patient can tolerate oral intake.

Flashcard 478: Drug of choice in pregnancy to prevent vertical transmission of Toxoplasmosis

Answer: Spiramycin

Flashcard 479: Drug of choice for ascariasis is :

Answer: Albendazole

Flashcard 480: Drug of choice for chloroquine-resistant malaria in the **1st trimester** of pregnancy is:

Answer: Quinine (+ Clindamycin)