Antimicrobial Agents — Flashcards

_____ is a NS3/4A protease inhibitor that may be used for the treatment of hepatitis C genotype 1

Pyrazinamide is activated to its active metabolite _____ in the host phagolysosome

Mutations in Mycobacterium tuberculosis that _____-regulate theexpression of KatG (a catalase-peroxidase) lead to Isoniazid resistance (drug)

_____ are a class of antifungals that inhibit the enzyme squalene epoxidase

_____ can be used to treat Chagas disease

Hint: which drug

_____ are antibiotics that require O2 to work, therefore do not work on obligate anaerobic bacteria

Clindamycin is actively transported into _____ and can be used to treat lung abscesses

For Malaria Chemoprophylaxis: Duration of travel is _____ than 6 weeks then doxycycline 100mg once a day can be started 2 days before travel and continued atleast 4 weeks after travel.

Adverse effects of the antifungal _____ includes blurry vision, changes in color vision, and flashes of light

_____ works by binding to bacterial DNA-dependent RNA polymerase, inhibiting RNA synthesis (antibacterial)