Analgesics and Anti-inflammatory Drugs — Flashcards

Flashcard 41: Drug of choice for rheumatoid arthritis is _______

Answer: Methotrexate

Flashcard 42: Drug of choice for chronic gout is

Answer: Allopurinol

Flashcard 43: What is the drug of choice for the treatment of an acute painful (vaso-occlusive) crisis in sickle cell anemia?

Answer: Morphine

Extra: Management of an acute sickle cell painful (vaso-occlusive) crisis includes: 1. **Aggressive Hydration**: To reduce blood viscosity. 2. **Analgesia**: Parenteral opioids are the mainstay. **Morphine** is generally considered the drug of choice for severe pain. 3. **Oxygenation**: If the patient is hypoxic. 4. **Treatment of Triggers**: Such as infections. *Note: **Hydroxyurea** is the drug of choice for the **prophylaxis** (prevention) of sickle cell crises, not for the acute treatment of a crisis.*

Flashcard 44: Drug of choice for acute gout is :

Answer: NSAIDs (e.g., Indomethacin)