Analgesics and Anti-inflammatory Drugs — Flashcards

Pain management for osteoarthritis includes acetaminophen, _____, Celecoxib and/or intra-articular glucocorticoids

Glucocorticoids may have anti-inflammatory effects via the inhibition of the release of _____ and serotonin from mast cells and platelets

_____ is an NSAID that is associated with tinnitus (ear) as an adverse effect

NSAIDs decrease prostaglandins, which normally _____ the afferent arterioles of the kidney

The effect of high dose aspirin _____ mg/day is anti inflammatory.

What are the two first-line drugs for the treatment of chronic gout? (underexcretion)_____

Triple therapy for rheumatoid arthritis is: _____methotrexate + sulfasalazine + hydroxychloroquine

At spinal level: opioids act in the substantia gelatinosa of the _____ horn to inhibit the release of excitatory transmitters like substance P from primary afferents carrying pain impulses

Glucocorticoids may have anti-inflammatory effects by inhibiting the production of _____ and thus inhibiting the proliferation of T lymphocytes

Cyclooxygenase-2 expression is _____ by inflammation