Renal Pathology — Flashcards

In _____, the combination of elevated PTH and decreased 1,25-(OH)2D3 produces renal osteodystrophy, in which there is increased bone resorption and osteomalacia

Patients with chronic interstitial nephritis have a _____ elevation of BUN and creatinine due to a mononuclear infiltrate of tubules causing fibrosis and atrophy

Minimal change disease is characterized by _____-mediated damage of foot processes and loss of glomerular basement anions

Damage to the glomerulus in Shigella-induced HUS results in platelet aggregation, _____ the platelet count when microthrombi form

Renal _____ is a benign encapsulated epithelial cell tumor arising from the intercalated cells of the collecting ducts (location)

Nephrotic syndrome occurs due to _____ damage disrupting the glomerular filtration charge barrier

_____ is characterized by a 'lumpy bumpy (granular)'' immunofluorescence pattern due to immune complex deposition

Patients with interstitial cystitis may under go transmural fibrosis later in the disease course, leading to _____ bladder

_____ cystitis occurs due to chronic irritation, such as from prolonged urinary retention, intravesical therapy, or BCG

Thin basement membrane lesion is characterised by diffuse thinning of the GBM, presenting with _____ w/o hearing loss or ocular abnormalities (unlike Alport syndrome)