Neuropathology — Flashcards

Flashcard 141: Medulloblastoma and malignant pinealoblastoma are WHO grade _____ tumors

Answer: IV

Extra: Both are highly malignant embryonal tumors (WHO Grade IV). Note: They are NOT astrocytomas.

Flashcard 142: What is the most common primary CNS tumor across all age groups?

Answer: Meningioma

Flashcard 143: Stage 4S is associated with a _____ prognosis in neuroblastoma

Answer: good

Flashcard 144: Optic nerve glioma (15-40%), a pilocytic astrocytoma, is commonly seen in _____

Answer: neurofibromatosis type 1 (inherited condition)

Flashcard 145: Anaplastic astrocytoma is a grade _____ astrocytoma

Answer: III

Flashcard 146: Leptomeningeal metastases, also known as _____, refers to the spread of malignant cells through the CSF space

Answer: carcinomatous meningitis

Flashcard 147: Most cases of primary glioblastoma are of the IDH-_____ type.

Answer: wild

Flashcard 148: Tuberculous caseous foci in brain, meninges and spinal cord is known as _____ focus.

Answer: Rich

Flashcard 149: TRKB expression is associated with a _____ prognosis in neuroblastoma

Answer: poor

Flashcard 150: Chromosome 1p and 11q losses are associated with a _____ prognosis in neuroblastoma

Answer: poor