Neuropathology — Flashcards

Flashcard 131: Medulloblastoma corresponds to WHO grade _____ CNS tumors

Answer: IV

Flashcard 132: _____ classification is used for classifying neuroblastoma.

Answer: Shimada

Flashcard 133: The _____ is most likely to show evidence of damage in the case of a hypoxic brain injury.

Answer: hippocampus (part of brain)

Flashcard 134: Is acoustic neuroma benign or malignant?_____

Answer: Benign

Flashcard 135: In meningiomas without NF2 mutations, the most common mutations occur in _____

Answer: TNF receptor-associated factor 7 (TRAF7)

Flashcard 136: Transcriptional repressor Capicua (CIC) mutations are found exclusively in which brain tumor?_____

Answer: Oligodendroglioma

Flashcard 137: _____ is characterized by the thickening and fibrosis of the arachnoid membrane

Answer: Arachnoiditis

Flashcard 138: What is the classical pathology seen in a child with spastic quadriplegia?

Answer: Parasagittal brain injury

Flashcard 139: What is the most common primary CNS tumor across all age groups?

Answer: Meningioma

Flashcard 140: Medulloblastoma and malignant pinealoblastoma are WHO grade _____ tumors

Answer: IV

Extra: Both are highly malignant embryonal tumors (WHO Grade IV). Note: They are NOT astrocytomas.