CNS Tumors — Flashcards

Flashcard 1: Meningioma is a _____ tumor of arachnoid cells

Answer: benign

Flashcard 2: Medulloblastoma and malignant pinealoblastoma are WHO grade _____ tumors

Answer: IV

Extra: Both are highly malignant embryonal tumors (WHO Grade IV). Note: They are NOT astrocytomas.

Flashcard 3: Neurofibromatosis type II is associated with mutations in the _____ tumor suppressor gene on chromosome 22

Answer: NF2

Flashcard 4: Optic nerve glioma (15-40%), a pilocytic astrocytoma, is commonly seen in _____

Answer: neurofibromatosis type 1 (inherited condition)

Flashcard 5: _____ is a primary CNS tumor characterized histologically by "fried egg" cells with a "chicken-wire" capillary pattern

Answer: Oligodendroglioma

Flashcard 6: What is the most common primary CNS tumor across all age groups?

Answer: Meningioma

Flashcard 7: _____ is the second most common adult primary intracranial neoplasm.

Answer: Glioblastoma

Flashcard 8: Glioblastoma multiforme (GBM) is a _____, high-grade tumor of astrocytes

Answer: malignant

Flashcard 9: What CNS tumor is seen in the histology slide below? _____

Answer: Hemangioblastoma (closely arranged, thin-walled capillaries with minimal intervening parenchyma)

Flashcard 10: Spheno-orbital encephalocoele, due to dysplasia of the greater wing of the sphenoid is commonly seen in _____

Answer: neurofibromatosis type 1