Hematopathology — Flashcards

Hemoglobin >_____ g/dL or Hematocrit >49% in men + bone marrow showing trilineage (or panmyelosis) growth +JAK2 mutation are major criteria for Polycythemia Vera

_____ is caused by an acquired defect in myeloid stem cells, resulting in absent GPI

_____ gene mutation present on chromosome 8p is the most common genetic mutation seen in autosomal-dominant hereditary spherocytosis

_____ test will help in diagnosis of factor XIII deficiency

_____ is associated with free light chain excretion in the urine, known as Bence Jones proteinuria

Hereditary stomatocytosis is caused by missense mutations in _____ or AEP

Hemophilia (A, B, C) presents with _____ PT and increased PTT

In -thalassemia major, 4 tetramers result in _____ erythropoiesis and extravascular hemolysis

_____ gene mutation present on chromosome 1q  is the most common genetic mutation seen in autosomal-recessive hereditary spherocytosis

Microangiopathic hemolytic anemia is seen in _____, HUS, and HELLP syndrome