Hematopathology — Flashcards

The typical normal values for a WBC differential (per USMLE) are:Neutrophils (~ _____%)Lymphocytes (~ 30%)Monocytes (~ 6%)Eosinophils (~ 3%)Basophils (~ 1%)

Multiple myeloma is associated with increased risk of _____ due to lack of antigenic diversity of monoclonal antibodies

_____ leukemia is associated with smudge cells and increased lymphocytes on blood smear

_____ leukemia causes marrow fibrosis, which results in a "dry tap" on bone marrow aspiration

-thalassemia mutations in -globin genes result in _____ or diminished (+) production of the -globin chain

_____ is due to inhibition or deficiency of the ADAMTS13 (vWF metalloprotease) enzyme

EBV-positive diffuse large-cell lymphoma is _____ for CD20, CD79a, IRF4/MUM1, LMP1 and CD15 negative

_____ is prolonged in all platelet disorders (both quantitative and qualitative)

Reed-Sternberg cells are classically positive for CD-_____ and CD-30

Myeloblasts may have crystal aggregates of _____, which are seen on blood smear as Auer rods