UPSC-CMS 2016 - Pharmacology PYQs Practice Questions

Q: Match List-I with List-II and select the correct answer using the code given below the Lists: **List-I (Anticancer Drugs)** A. Cisplatinum B. Adriamycin C. Bleomycin D. Cyclophosphamide **List-II (Adverse Effects)** 1. Pulmonary fibrosis 2. Haemorrhagic cystitis 3. Tubular necrosis 4. Cardiomyopathy

A→3 B→4 C→1 D→2. ***A→3 B→4 C→1 D→2*** - This option correctly matches each anticancer drug to its characteristic adverse effect: **Cisplatinum (A)** with **tubular necrosis (3)**, **Adriamycin (B)** with **cardiomyopathy (4)**, **Bleomycin (C)** with **pulmonary fibrosis (1)**, and **Cyclophosphamide (D)** with **haemorrhagic cystitis (2)**. - These drug-toxicity associations are clinically important for monitoring and managing patients on chemotherapy. *A→3 B→4 C→2 D→1* - This option incorrectly matches Bleomycin with haemorrhagic cystitis (should be pulmonary fibrosis) and Cyclophosphamide with pulmonary fibrosis (should be haemorrhagic cystitis). - While Cisplatinum and Adriamycin are correctly paired, the last two associations are reversed. *A→4 B→3 C→2 D→1* - This option incorrectly matches Cisplatinum with cardiomyopathy (should be tubular necrosis) and Adriamycin with tubular necrosis (should be cardiomyopathy). - Additionally, Bleomycin and Cyclophosphamide complications are also incorrectly paired. *A→4 B→3 C→1 D→2* - This option incorrectly swaps the complications for Cisplatinum and Adriamycin: Cisplatinum is matched with cardiomyopathy (should be tubular necrosis) and Adriamycin with tubular necrosis (should be cardiomyopathy). - While Bleomycin and Cyclophosphamide are correctly paired with their respective complications, the first two associations are incorrect. [Practice more Pharmacology PYQs on OnCourse]

Q: Match List-I with List-II and select the correct answer using the code given below the Lists:

A→4 B→3 C→2 D→1. ***A→4 B→3 C→2 D→1*** - This option correctly matches **Stomach poison** with **Sodium fluoride** (4), **Organochlorine compound** with **Dieldrin** (3), **Organophosphorus compound** with **Temephos** (2), and **Carbamates** with **Propoxur** (1). - **Sodium fluoride** acts as a stomach poison requiring ingestion, **Dieldrin** is a persistent organochlorine insecticide, **Temephos** is an organophosphorus compound used for larval control, and **Propoxur** is a carbamate insecticide for household pest control. *A→4 B→3 C→1 D→2* - This option incorrectly matches **Organophosphorus compound** with **Propoxur** (1), which is actually a **carbamate**, not an organophosphorus compound. - It also incorrectly matches **Carbamates** with **Temephos** (2), which is actually an **organophosphorus** compound, not a carbamate. *A→3 B→4 C→2 D→1* - This option incorrectly matches **Stomach poison** with **Dieldrin** (3), which is an **organochlorine compound**, not a stomach poison. - It also incorrectly matches **Organochlorine compound** with **Sodium fluoride** (4), which functions as a **stomach poison**, not an organochlorine compound. *A→3 B→4 C→1 D→2* - This option creates multiple incorrect matches: **Stomach poison** with **Dieldrin** (3) instead of **Sodium fluoride**, and **Organochlorine compound** with **Sodium fluoride** (4) instead of **Dieldrin**. - It also incorrectly swaps the organophosphorus and carbamate matches, placing **Propoxur** with organophosphorus and **Temephos** with carbamates. [Practice more Pharmacology PYQs on OnCourse]

Question 1

Match List-I with List-II and select the correct answer using the code given below the Lists:

**List-I (Anticancer Drugs)**
A. Cisplatinum
B. Adriamycin
C. Bleomycin
D. Cyclophosphamide

**List-II (Adverse Effects)**
1. Pulmonary fibrosis
2. Haemorrhagic cystitis
3. Tubular necrosis
4. Cardiomyopathy

Accepted Answer

A→3  B→4  C→1  D→2

Answer

A→3  B→4  C→2  D→1

Answer

A→4  B→3  C→2  D→1

Answer

A→4  B→3  C→1  D→2

Question 2

Match List-I with List-II and select the correct answer using the code given below the Lists:

Accepted Answer

A→4  B→3  C→2  D→1

Answer

A→4  B→3  C→1  D→2

Answer

A→3  B→4  C→2  D→1

Answer

A→3  B→4  C→1  D→2

UPSC-CMS 2016 — Pharmacology