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FMGE 2011 — Pharmacology

Q: All are true about atropine poisoning, except

Decreased temperature. ***Decreased temperature*** - Atropine is an **anticholinergic** agent that blocks muscarinic receptors, leading to decreased sweating and **hyperthermia** (increased temperature) in poisoning. - The phrase **"hot as a hare"** is a classic mnemonic for atropine poisoning, referring to this elevated body temperature. *Dysarthria* - **Dysarthria** (slurred or difficult speech) can be a symptom of atropine poisoning due to the **CNS effects** of anticholinergic toxicity. - Atropine crosses the blood-brain barrier and can cause a range of neurological symptoms including agitation, delirium, and impaired speech. *Dysphagia* - **Dysphagia** (difficulty swallowing) is a common symptom in atropine poisoning, related to the **drying of oral and pharyngeal secretions** due to anticholinergic effects. - The mouth becomes very dry, making it difficult to form a food bolus and swallow effectively. *Dilated pupils* - **Dilated pupils (mydriasis)** unresponsive to light are a hallmark sign of atropine poisoning, as atropine blocks parasympathetic innervation to the iris sphincter muscle. - This symptom is often described in the mnemonic as **"blind as a bat"** due to the associated blurred vision and photophobia. [Practice more Pharmacology PYQs on OnCourse]

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All are true about atropine poisoning, except

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