85% OFFLimited time offer

Enter your email to get your 85% OFF code and unlock the full NEET PG question bank on the app.

85% OFFLimited time offer

Back to FMGE 2011

FMGE 2011 — Biochemistry

Q: Fluoride, used in the collection of blood samples, inhibits which enzyme?

Enolase. ***Enolase*** - Fluoride is a potent inhibitor of **enolase**, an enzyme in the **glycolytic pathway**. - Inhibition of enolase prevents the conversion of **2-phosphoglycerate** to **phosphoenolpyruvate**, thereby halting glycolysis in collected blood samples. *Glucokinase* - Glucokinase is an enzyme primarily found in the **liver** and **pancreatic beta cells** that phosphorylates glucose. - Fluoride does not directly inhibit glucokinase; its primary site of action for preventing glycolysis in blood samples is enolase. *Glucose-6-phosphatase* - This enzyme is crucial for **glucose production** in the liver and kidneys, facilitating the dephosphorylation of **glucose-6-phosphate** to glucose. - Fluoride does not specifically target glucose-6-phosphatase as its mechanism for preventing glycolysis. *Hexokinase* - Hexokinase catalyzes the first step of glycolysis, phosphorylating **glucose to glucose-6-phosphate**. - While essential for glycolysis, hexokinase is not the primary target of fluoride's inhibitory action in blood collection, which specifically aims to stop the entire pathway further downstream at enolase. [Practice more Biochemistry PYQs on OnCourse]

1 Previous Year Questions with Answers & Explanations

Questions

All Subjects Biochemistry (1)Dental (1)Forensic Medicine (3)Internal Medicine (1)Obstetrics and Gynecology (1)Pathology (1)Pediatrics (1)Pharmacology (1)Psychiatry (2)Radiology (1)Surgery (1)

Fluoride, used in the collection of blood samples, inhibits which enzyme?

FMGE 2011 Biochemistry PYQs | 1+ Solved MCQs – Oncourse AI