Genetics and Disease — MCQs

Q: In Kartagener syndrome, the cause of infertility is?

Asthenospermia. ***Asthenospermia*** - In Kartagener syndrome, **dynein arms** in sperm flagella are defective, leading to **poor sperm motility**. - This severely impairs the sperm's ability to reach and fertilize an egg, resulting in **infertility**. *Oligospermia* - This refers to a **low sperm count** and is not the primary cause of infertility in Kartagener syndrome. - While overall semen quality can be affected, the central issue is the **lack of sperm movement**, not insufficient numbers. *Undescended testis* - Also known as **cryptorchidism**, this condition involves one or both testes failing to descend into the scrotum. - It leads to impaired sperm production due to higher intra-abdominal temperatures, but is unrelated to the **ciliary dysfunction** seen in Kartagener syndrome. *Epididymal obstruction* - This involves a blockage in the **epididymis**, preventing sperm from being ejaculated. - While it causes infertility, it is a structural problem and does not account for the **motility defects** seen in Kartagener syndrome.

Practice by Chapter

Principles of Medical Genetics

Practice Questions

Genetic Testing and Counseling

Practice Questions

Single Gene Disorders

Practice Questions

Chromosomal Disorders

Practice Questions

Mitochondrial Diseases

Practice Questions

Pharmacogenomics

Practice Questions

Cancer Genetics

Practice Questions

Genetics of Common Diseases

Practice Questions

Epigenetics and Disease

Practice Questions

Genetic Basis of Developmental Disorders

Practice Questions

Ethical Issues in Medical Genetics

Practice Questions

Gene Therapy and Precision Medicine

Practice Questions

Want unlimited practice?

Get full access to all questions, explanations, and performance tracking.

Start For Free

Scan to download app