FMGE 2023 - Pediatrics PYQs Practice Questions

Q: Following urine microscopy and examination, a child is found to have hematuria and RBC casts in the urine. What is the probable cause for this?

Post-streptococcal glomerulonephritis (PSGN). ***Post-streptococcal glomerulonephritis (PSGN)***- RBC casts are highly indicative of **active glomerulonephritis**, demonstrating that red blood cells have leaked through damaged glomeruli and aggregated in the renal tubules.- **PSGN** is the most common cause of acute nephritic syndrome in children, typically following a *Streptococcal* infection, characterized by **hematuria**, hypertension, and mild proteinuria.*Focal segmental glomerulosclerosis (FSGS)*- FSGS almost universally presents as **nephrotic syndrome**, characterized by heavy **proteinuria**, profound edema, and hypoalbuminemia.- While microscopic hematuria may be present, the finding of **RBC casts** is highly uncommon and points away from a primary diagnosis of FSGS.*Membranoproliferative glomerulonephritis (MPGN)*- MPGN often presents with a **mixed nephrotic and nephritic picture**, including hematuria, but is less common acutely than PSGN in children.- PSGN presents with a very typical acute onset of **nephritic features** (hematuria, casts, hypertension) following infection, making it the more probable cause.*Minimal change disease*- This is the leading cause of **nephrotic syndrome** in children, defined by massive **proteinuria** with minimal to no damage visible on light microscopy.- **Minimal change disease** classically presents without significant hematuria and **RBC casts** are virtually absent. [Practice more Pediatrics PYQs on OnCourse]

Q: Which of the following is not true about CHPS? CHPS - Congenital hypertrophic pyloric stenosis

b.Caused by hypertrophy of longitudinal muscles. ***b.Caused by hypertrophy of longitudinal muscles***- The defining pathology of congenital hypertrophic pyloric stenosis involves hypertrophy and hyperplasia of the **circular muscle layer** of the pylorus, not the longitudinal muscle layer.- This thickening of the circular muscle narrows the pyloric canal lumen, leading to gastric outlet obstruction.*a.Presents with non-bilious vomiting*- This is a true statement; vomiting is typically **non-bilious** because the obstruction is proximal to the **ampulla of Vater** (where bile enters the duodenum).- The vomiting is often projectile, feeding soon after a meal, and progresses from occasional to nearly every feed.*c.USG is very sensitive in diagnosing this condition*- This is a true statement; ultrasonography is the diagnostic modality of choice due to its high sensitivity and specificity, avoiding radiation exposure.- Diagnosis is confirmed when the **pyloric muscle wall thickness** is >4 mm or the **pyloric channel length** is >16 mm.*d.Hypokalemic metabolic alkalosis seen*- This is a true statement; persistent, massive vomiting leads to the loss of gastric **hydrochloric acid (HCl)**.- The resulting primary loss of H+ ions leads to **metabolic alkalosis**, which is compensated by renal excretion of K+ and retention of HCO3- (leading to secondary **hypokalemia**). [Practice more Pediatrics PYQs on OnCourse]

Q: How much oxygen is given to a term infant with respiratory distress during resuscitation?

21%. ***Correct: 21% (Room Air)*** - **Current NRP and WHO guidelines** recommend starting resuscitation of **term infants with 21% oxygen (room air)** - Evidence shows room air is **equally effective** as 100% oxygen for initial resuscitation - Reduces **oxidative stress and potential harm** from hyperoxia - Oxygen can be **titrated up** if preductal SpO2 targets are not achieved within expected timeframes - This applies specifically to **term infants (≥37 weeks gestation)** *Incorrect: 70%* - Not a standard concentration used in neonatal resuscitation - Would expose infant to unnecessarily high oxygen levels without clear benefit *Incorrect: 100%* - **Outdated practice** - previously used but no longer recommended for term infants - Associated with increased **oxidative stress** and potential harm - May still be considered for **preterm infants <35 weeks** (start with 21-30% and titrate) *Incorrect: 50%* - Not the recommended starting concentration for term infants - May be used as an **intermediate step** when titrating oxygen if initial room air is insufficient **Key Point:** For term infants, always start with room air (21%) during resuscitation and titrate based on SpO2 targets. [Practice more Pediatrics PYQs on OnCourse]

Q: Which of the following is an absolute contraindication for breastfeeding?

Galactosemia in infant. ***Galactosemia in infant***- **Galactosemia** is an absolute contraindication as the infant lacks the enzyme needed to metabolize **galactose** found in breast milk (**lactose**).- Ingestion of breast milk leads to the accumulation of toxic metabolites, potentially causing **liver failure**, **cataracts**, and **developmental delay**.*HIV positive mother*- In resource-rich settings, **HIV** is generally considered a contraindication, but it is not universally absolute; in low-resource settings, exclusive breastfeeding might be recommended if formula feeding is unsafe.- Effective maternal **Antiretroviral Therapy (ART)** significantly reduces the risk of transmission via breast milk, making it a relative risk based on local context and ART adherence.*Hepatitis C in mother*- **Hepatitis C virus (HCV)** is generally **not transmitted** through breast milk, and breastfeeding is usually considered safe.- Breastfeeding is only cautioned against if the mother has **bleeding or fissured nipples**, which could theoretically allow blood-borne virus transmission.*Tuberculosis in mother*- Mothers with routine, **active pulmonary TB** can breastfeed if they are on appropriate treatment and wear a mask, as the bacteria is rarely excreted in milk.- If the mother has newly diagnosed, **untreated active TB**, temporary separation and feeding expressed milk may be necessary until she is non-infectious, but breastfeeding is not permanently contraindicated. [Practice more Pediatrics PYQs on OnCourse]

Q: An 8-year-old child presented with a sudden onset of high-grade fever, seizures, and loss of consciousness. On examination, the child had anemia, hypoglycemia, and no focal neurological deficits. What is the probable diagnosis?

Cerebral malaria. ***Cerebral malaria***- This diagnosis is strongly suggested by the sudden onset of high-grade fever, seizures, and loss of consciousness in a child, coupled with systemic complications like **anemia** and significant **hypoglycemia**.- Cerebral malaria, caused by *Plasmodium falciparum*, is a medical emergency where **hypoglycemia** results from high glucose consumption by parasites and impaired hepatic gluconeogenesis; **anemia** is also a key feature. *Tubercular meningitis*- Tuberculous meningitis typically presents with an **insidious, subacute onset** (over weeks) of fever, headache, and altered sensorium, not the sudden, explosive presentation described.- While it can cause neurological deficits, it is less commonly associated with the acute, severe systemic triad of high fever, profound **hypoglycemia**, and **anemia** seen here.*Viral meningitis*- Viral meningitis is usually associated with a milder clinical course and typically lacks the profound systemic complications like severe **anemia** and significant **hypoglycemia** that often precipitate seizures and coma in this age group.- Though high fever and seizures can occur, the presence of severe systemic features points away from typical viral etiologies and towards a systemic parasitic infection.*Fungal meningitis*- Fungal meningitis (e.g., *Cryptococcus*) is typically an **indolent or chronic infection** developing over weeks to months, primarily affecting **immunocompromised patients** (e.g., HIV/AIDS), which is unlikely in an otherwise healthy 8-year-old.- It rarely presents as an acute febrile illness with subsequent rapid onset of **anemia** and severe **hypoglycemia** leading to loss of consciousness. [Practice more Pediatrics PYQs on OnCourse]

Question 1

Following urine microscopy and examination, a child is found to have hematuria and RBC casts in the urine. What is the probable cause for this?

Accepted Answer

Post-streptococcal glomerulonephritis (PSGN)

Answer

Focal segmental glomerulosclerosis (FSGS)

Answer

Membranoproliferative glomerulonephritis (MPGN)

Answer

Minimal change disease

Question 2

Which of the following is not true about CHPS? CHPS - Congenital hypertrophic pyloric stenosis

Accepted Answer

b.Caused by hypertrophy of longitudinal muscles

Answer

a.Presents with non-bilious vomiting

Answer

c.USG is very sensitive in diagnosing this condition

Answer

d.Hypokalemic metabolic alkalosis seen

Question 3

How much oxygen is given to a term infant with respiratory distress during resuscitation?

Accepted Answer

21%

Answer

70%

Answer

100%

Answer

50%

Question 4

Which of the following is an absolute contraindication for breastfeeding?

Accepted Answer

Galactosemia in infant

Answer

HIV positive mother

Answer

Tuberculosis in mother

Answer

Hepatitis C in mother

Question 5

An 8-year-old child presented with a sudden onset of high-grade fever, seizures, and loss of consciousness. On examination, the child had anemia, hypoglycemia, and no focal neurological deficits. What is the probable diagnosis?

Accepted Answer

Cerebral malaria

Answer

Tubercular meningitis

Answer

Viral meningitis

Answer

Fungal meningitis

Question 6

Gonadal growth corresponds with _____.

Accepted Answer

Skeletal system

Answer

Dental growth

Answer

Lymphoid growth

Answer

Brain

Question 7

A 6-year-old child is brought for complaints of short stature. His height is comparable with his parent's height and his bone age corresponds to his chronological age. What is the likely diagnosis?

Accepted Answer

Familial short stature

Answer

Constitutional delay

Answer

Undernutrition

Answer

Growth hormone deficiency

Question 8

A 5-year-old child presented with recurrent respiratory infections with thickened sputum. Chest X-ray showed bronchial wall thickening. He has been suffering from steatorrhea since birth. Which of the following is the first differential diagnosis?

Accepted Answer

Cystic fibrosis

Answer

Hyaline membrane disease

Answer

Alpha 1 anti-trypsin deficiency

Answer

Malabsorption syndrome

Question 9

A child presents with the findings shown in the image below. What is the true statement regarding this condition?

Accepted Answer

Kwashiorkor due to protein malnutrition

Answer

Kwashiorkor due to calorie malnutrition

Answer

Marasmus due to calorie malnutrition

Answer

Marasmus due to protein malnutrition

Question 10

A 5-year-old girl is brought to the clinic with a fever, cough, red eyes, running nose, and rash. The appearance of the child is shown below. What is the diagnosis? ![img-36.jpeg](img-36.jpeg)

Accepted Answer

Measles

Answer

Chickenpox

Answer

Mumps

Answer

Erythema infectiosum

FMGE 2023 — Pediatrics