Renal — Flashcards

Flashcard 121: The _____ is responsible for approximately 8% of Ca2+ reabsorption

Answer: distal tubule

Flashcard 122: The region of substance clearance (e.g. glucose) between threshold and Tm is known as _____

Answer: splay

Flashcard 123: Why does hypocalcemia cause symptoms such as tingling/numbness and twitching/cramping? _____

Answer: Decreased extracellular Ca2+ decreases the threshold potential (makes it more negative)

Flashcard 124: PTH action causes _____-calciuria

Answer: hypo

Flashcard 125: The [TF/P]creatinine ratio greatly _____ over the course of the PCT

Answer: increases

Flashcard 126: Loop diuretics cause _____ hypertonicity of the renal medulla

Answer: decreased

Extra: First Aid Pharmacology: Renal (Diuretics)

Flashcard 127: How does ADH increase H2O permeability of the principal cells of the late distal tubule and collecting duct? Increased _____ channels via increased _____

Answer: aquaporin 2 (AQP2)

Flashcard 128: The _____ is the gradient of osmolarity from the cortex (300 mOsm/L) to the papilla (1200 mOsm/L)

Answer: corticopapillary osmotic gradient

Flashcard 129: Which renal tubular acidosis is associated with increased urinary excretion of HCO3-? _____

Answer: Proximal RTA (type 2)

Extra: * due to decreased reabsorption of bicarb (85% of bicarb is rebsorbed at the PCT)

Flashcard 130: Following the thin descending limb, glomerular filtrate enters the _____

Answer: thin ascending limb (loop of Henle)

Extra: Atlas: