Gas exchange — Flashcards

Flashcard 11: Factors that shift the O2-Hb dissociation curve to the _____ favor the taut form of hemoglobin

Answer: right

Flashcard 12: One major effect of thyroid hormone is increased _____ with a resultant increase in BMR and body temperature, due to increased Na/K+-ATPase activity

Answer: O2 consumption

Flashcard 13: The diffusion coefficient (DK) for CO2 is approximately 20x _____ than that of O2

Answer: higher

Flashcard 14: If CO2 production is constant, then the arterial and alveolar Pco2 is determined by _____

Answer: alveolar ventilation

Flashcard 15: According to Fick's law, the rate of diffusion of a gas ($V_{gas}$) is equal to: _____

Answer: $\frac{A \cdot D \cdot \Delta P}{T}$

Extra: The formula can also be expressed as $V_{gas} = D_L \cdot \Delta P$, where $D_L$ is the lung diffusing capacity (which incorporates area, thickness, and the diffusion constant). $D_L$ is decreased in conditions like emphysema (decreased area) or pulmonary fibrosis (increased thickness).

Flashcard 16: When using the alveolar gas equation, the respiratory quotient (R) is equal to the ratio of _____ / _____

Answer: CO2 produced

Flashcard 17: _____ O2 binding to hemoglobin causes increased affinity for CO2 and H+ (Haldane effect)

Answer: Decreased

Flashcard 18: The lung diffusing capacity (DL) can be measured with _____ because it is exclusively diffusion-limited

Answer: carbon monoxide (CO)

Flashcard 19: Is the A - a gradient normal, increased, or decreased, in response to diffusion defects (e.g. fibrosis, pulmonary edema)? _____

Answer: Increased

Flashcard 20: CO exhibits _____-limited gas exchange

Answer: diffusion