Oxygen transport in blood — Flashcards

Flashcard 1: Patients with cyanide poisoning have a _____ of the venous-arterial PO2 gradient

Answer: narrowing

Flashcard 2: Why must fetal hemoglobin have a much higher O2 binding affinity than HbA? _____

Answer: Drives O2 diffusion across placenta from mother to fetus

Flashcard 3: Carbon monoxide binds competitively to Hb and with 200-250x _____ affinity than O2

Answer: greater

Flashcard 4: Blood in the umbilical vein has a Po2 of approximately _____ mmHg

Answer: 30

Flashcard 5: One way in which CO2 is carried in the blood is bound to hemoglobin, known as _____ (5%)

Answer: carbaminohemoglobin (HbCO2)

Flashcard 6: Carboxyhemoglobin heme groups not bound by CO have a(n) _____ affinity for O2

Answer: increased

Flashcard 7: What is the secondary regulator of cerebral perfusion?

Answer: PO2 - only takes effect during severe hypoxia

Flashcard 8: What is the primary regulator of cerebral perfusion?

Answer: PCO2

Flashcard 9: How long can the brain withstand hypoxia before sustaining irreversible damage?

Answer: 5 minutes

Flashcard 10: In the _____, HCO3- enters the red blood cells in exchange for Cl-

Answer: lungs

Extra:  Watch associated Bootcamp video [https://app.bootcamp.com/med-school/pulmonology/videos/blood?index=12] https://onlinemeded.org?ref=anki