Antivirals — Flashcards

Flashcard 271: Which type of HAART drug is Ritonavir?_____

Answer: Protease inhibitor

Flashcard 272: Which NRTI is a nucleo**tide** and thus bypasses the **initial** phosphorylation step?

Answer: Tenofovir

Extra: Most NRTIs are nucleo**s**ides and require three phosphorylation steps (by host cell kinases) to become active. Tenofovir is a nucleo**tide** (nucleoside monophosphate analog) and thus bypasses the initial phosphorylation step.

Flashcard 273: Which type of HAART drug is Maraviroc?

Answer: Entry inhibitor (CCR5 antagonist)

Flashcard 274: Which HAART drug class commonly causes lipodystrophy?_____

Answer: Protease inhibitors

Flashcard 275: Which type of vaccine has the potential to revert to a virulent form? _____

Answer: Live, attenuated vaccines

Flashcard 276: Protease inhibitors can result in hyperglycemia due to _____ resistance

Answer: insulin

Flashcard 277: Which type of HAART drug is tenofovir (TDF)?_____

Answer: NRTI

Flashcard 278: Which subtypes of HPV are covered by the current quadrivalent vaccine?_____

Answer: HPV6, 11, 16, 18

Flashcard 279: What type of vaccine is the yellow fever vaccine? _____

Answer: Live attenuated

Flashcard 280: What type of vaccine is the MMR vaccine?_____

Answer: Live, attenuated