Antivirals — Flashcards

HCV therapeutics with the suffix _____ work by inhibiting the NS5A protein, which plays an integral role in viral replication

Abacavir (ABC) is contraindicated for HIV treatment if patient has an HLA-_____ mutation

Cidofovir preferentially inhibits viral _____ polymerase

Mycophenolate Mofetil is associated with invasive _____ infections

Which antiviral can cause seizures due to electrolyte disturbances? _____

Which viral DNA-polymerase inhibitors do not require thymidine kinase to become active? _____

What drug is a pyrophosphate analog that directly inhibits viral DNA polymerase? _____

Which HIV protease inhibitor displays the most potent inhibition of CYP450? _____

The inactivated influenza vaccine results in humoral (antibody) response to the _____ antigen

Rituximab is associated with a rapidly fatal neuropathology known as Progressive Multifocal Leukoencephalopathy due to reactivation of the _____ virus