Antifungals US Medical PG Flashcards - Medical Study Cards
Master Antifungals with OnCourse flashcards. These spaced repetition flashcards are designed for medical students preparing for NEET PG, USMLE Step 1, USMLE Step 2, MBBS exams, and other medical licensing examinations.
Antifungals Flashcard Deck - 10 Cards
Flashcard 51: _____azole is used for systemic infections with dimorphic fungi
Answer: Itracon
Extra:
https://onlinemeded.org/spa/microbiology/fungi/acquire?ref=anki
Flashcard 52: Azoles inhibit the conversion of _____ to _____
Answer: lanosterol
Extra:
Watch Azoles [https://dashboard.sketchy.com/study/medical/courses/medical-pharmacology/units/medical-pharmacology-antimicrobials/videos/medical-pharmacology-antimicrobials-antifungals-azoles?utm_source=anki&utm_medium=partnership&utm_campaign=february_update&utm_content=medical]
https://onlinemeded.org/spa/microbiology/fungi/acquire?ref=anki
Flashcard 53: Griseofulvin is a(n) _____ of CYP-450
Answer: inducer
Extra:
https://onlinemeded.org/spa/pediatrics/seizures/acquire?ref=anki
Flashcard 54: Azoles can cause anti-androgenic side effects, most commonly resulting in _____
Answer: gynecomastia
Extra:
https://onlinemeded.org/spa/microbiology/fungi/acquire?ref=anki
Flashcard 55: Terbinafine is associated with side effects of GI upset, headaches, hepatotoxicity, and _____ disturbance
Answer: taste
Extra:
Watch Griseofulvin, Terbinafine, Echinocandins [https://dashboard.sketchy.com/study/medical/courses/medical-pharmacology/units/medical-pharmacology-antimicrobials/videos/medical-pharmacology-antimicrobials-antifungals-griseofulvin-terbinafine-echinocandins?utm_source=anki&utm_medium=partnership&utm_campaign=february_update&utm_content=medical]
https://onlinemeded.org/spa/microbiology/fungi/acquire?ref=anki
Flashcard 56: Which antifungal is fungistatic?
_____
Answer: Griseofulvin
Extra:
https://onlinemeded.org/spa/microbiology/fungi/acquire?ref=anki
Flashcard 57: Azoles work by inhibiting _____ enzymes in the Fungi
Answer: cytochrome P450
Extra: Ergosterol is a component of the fungal cell membrane. The cell wall contains chitin and β-glucans (targeted by echinocandins).
Flashcard 58: _____ (e.g., Amphotericin B, Nystatin) disrupt fungal cell membrane integrity by binding to ergosterol and forming pores.
Answer: Polyenes
Extra: Mechanism: Bind ergosterol (unique to fungi); form membrane pores that allow leakage of electrolytes.
Flashcard 59: Local, mild infections of Blastomycosis are treated with _____ drugs, e.g. _____
Answer: -azole
Extra:
Watch Blastomyces dermatitidis [https://dashboard.sketchy.com/study/medical/courses/medical-microbiology/units/medical-microbiology-fungi/videos/medical-microbiology-fungi-systemic-mycoses-blastomyces-dermatitidis?utm_source=anki&utm_medium=partnership&utm_campaign=february_update&utm_content=medical]
https://onlinemeded.org/spa/microbiology/fungi/acquire?ref=anki
Flashcard 60: To decrease toxicity of amphotericin B, use a(n) _____ formulation and give with IV normal saline
Answer: liposomal
Extra:
https://onlinemeded.org/spa/microbiology/fungi/acquire?ref=anki
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