Antifungals — Flashcards

Flashcard 41: Which antifungal has a cross-reactivity with penicillin hypersensitivity? _____

Answer: Griseofulvin

Flashcard 42: Griseofulvin will _____ serum levels of warfarin

Answer: decrease

Flashcard 43: Which antifungal inhibits cortisol production? _____

Answer: Ketoconazole

Flashcard 44: Use of Griseofulvin is contraindicated in _____ and/or _____ women

Answer: pregnant

Flashcard 45: Flucytosine is activated intracellularly to _____ by cytosine deaminase

Answer: 5-fluorouracil (5-FU)

Flashcard 46: _____ deposits in keratin-containing tissues, such as skin and nails, and is therefore used for severe dermatophyte infections

Answer: Griseofulvin

Flashcard 47: Echinocandins are primarily indicated for _____ infections of Aspergillosis and Candida

Answer: invasive

Flashcard 48: Which antifungal is contraindicated in patients with porphyrias? _____

Answer: Griseofulvin

Flashcard 49: Terbinafine inhibits the enzyme _____.

Answer: squalene epoxidase

Extra: Used primarily for dermatophytoses (e.g., onychomycosis).

Flashcard 50: Nystatin is active against _____ spp.

Answer: Candida