Antibiotics — Flashcards

Flashcard 361: Sulbactam is an irreversible β-lactamase inhibitor that is combined with _____ (Unasyn)

Answer: ampicillin (an aminopenicillin)

Flashcard 362: What drug is first-line in the treatment of Lyme disease? _____

Answer: Doxycycline

Flashcard 363: Resistance to Aminoglycosides is encoded by bacterial _____ enzymes

Answer: transferase

Flashcard 364: Bacitracin works by inhibiting Bactoprenol, a peptidoglycan "building block" _____ molecule

Answer: carrier

Flashcard 365: What is used for prophylaxis of Leptospirosis? _____

Answer: Doxycycline

Flashcard 366: Is the recurrence rate of C. difficile colitis lower or higher when taking Fidaxomicin than with vancomycin? _____

Answer: Significantly lower

Flashcard 367: In pregnant women and children with early localized Lyme disease (*Borrelia burgdorferi*), preferred oral alternatives to doxycycline include _____ or _____

Answer: amoxicillin

Extra: Doxycycline is avoided in pregnancy and young children (classically <8 years) due to the risk of fetal/childhood tooth discoloration and effects on bone growth.

Flashcard 368: What cephalosporin is used as prophylaxis before abdominal surgery? _____

Answer: Cefoxitin (cephamycin group)

Flashcard 369: C. difficile pseudomembranous colitis is classically linked to which protein synthesis inhibiting antibiotic? _____

Answer: Clindamycin

Flashcard 370: _____ is a cephalosporin that can be used to treat endocarditis by S. viridans and "HACEK" organisms

Answer: Ceftriaxone