Inflammation — Flashcards

Flashcard 141: Which cells release proteolytic enzymes in response to brain abscess, causing liquefactive necrosis? _____

Answer: Neutrophils

Flashcard 142: Pseudogout is caused by deposition of _____ crystals in tissues, especially the joints

Answer: calcium pyrophosphate

Extra: *Hyaline cartilage that covers the articular surfaces of moveable joints is termed articular cartilage Atlas:

Flashcard 143: In IgM-mediated hemolytic anemia, RBCs inactivate complement but residual C3b serves as an opsonin for splenic macrophages, resulting in _____ formation

Answer: spherocyte

Extra: * Error in sketchy- confirmed with Uworld Other:

Flashcard 144: TNF-α is a cytokine released from _____ that mediates cachexia and shock

Answer: macrophages

Flashcard 145: One cardinal sign of inflammation is _____, or warmth

Answer: calor

Flashcard 146: Cellular adhesion molecules (CAMs) on endothelial cells bind _____ on leukocytes, resulting in firm adhesion to the vessel wall

Answer: integrins

Extra: UWorld:

Flashcard 147: Chronic granulomatous disease (CGD) can present with granulomas (may contain multinucleated giant cells) in _____

Answer: any organs

Flashcard 148: Psoriasis may be associated with _____, which are collections of neutrophils in the stratum corneum

Answer: Munro microabscesses

Extra: Atlas:

Flashcard 149: Serum sickness-like reactions are associated with some drugs acting as _____ and infections (ex. HBV)

Answer: haptens (ex. penicillin)

Flashcard 150: Which inflammatory dermatitis presents with hypergranulosis? _____

Answer: Lichen planus

Extra: * Hypergranulosis is defined as increased thickness of the stratum granulosum (e.g. Lichen planus) Atlas: