Cell injury — Flashcards

Flashcard 231: What cause of free radical injury occurs following thrombolytic therapy? _____

Answer: Reperfusion injury

Flashcard 232: _____ membrane damage in irreversible cell injury results in hydrolytic enzymes leaking into the cytosol

Answer: Lysosome

Flashcard 233: Which cells release proteolytic enzymes in response to brain abscess, causing liquefactive necrosis?_____

Answer: Neutrophils

Flashcard 234: What is the standard screening test for G6PD deficiency?

Answer: Fluorescent spot test

Extra: The methemoglobin reduction test is another screening option. Heinz bodies (denatured hemoglobin) are visualized using supravital stains like crystal violet during an acute hemolytic episode. The definitive/confirmatory test is a quantitative G6PD enzyme assay.

Flashcard 235: What type of red blood cell is associated with microangiopathic hemolytic anemia? _____

Answer: Schistocytes ("helmet cells")

Flashcard 236: Which type of necrosis is characterized by soft, friable necrotic tissue with a "cottage cheese-like" appearance? _____

Answer: Caseous necrosis

Flashcard 237: What type of infarct occurs in tissues with a single arterial blood supply (e.g. heart, kidney, spleen)? _____

Answer: Pale (anemic) infarct

Flashcard 238: Which cellular change is characterized by a decrease in tissue mass due to decrease in size or number of cells? _____

Answer: Atrophy

Flashcard 239: Which feature of cell death is characterized by nuclear condensation? _____

Answer: Pyknosis

Flashcard 240: Which type of calcification (dystrophic or metastatic) tends to be localized? _____

Answer: Dystrophic