Cell injury — Flashcards

Flashcard 221: Which mechanism of cell death is an inflammatory process? _____

Answer: Necrosis

Flashcard 222: Is the neuronal injury due to cerebral ischemia reversible or irreversible? _____

Answer: Irreversible

Flashcard 223: Fat necrosis of breast tissue is usually related to _____, but a history of such is not always reported

Answer: trauma

Flashcard 224: CMV can present with inclusion bodies said to look like _____

Answer: "owl's eyes"

Flashcard 225: In burns, the zone of stasis / edema has decreased perfusion due to _____

Answer: microvascular thrombosis

Flashcard 226: What type of necrosis may be seen with gangrenous necrosis if superinfection occurs? _____

Answer: Liquefactive necrosis ("wet gangrene")

Flashcard 227: The coarse yellowish-brown pigment in hepatocytes / kupffer cells from hemochromatosis may be distinguished from lipofuscin by staining with _____

Answer: Prussian blue

Flashcard 228: In addition to the brain, what other organ may undergo liquefactive necrosis? _____

Answer: Pancreas

Flashcard 229: The morphologic hallmark of cell death is loss of the _____

Answer: nucleus

Flashcard 230: What is the standard screening test for G6PD deficiency?

Answer: Fluorescent spot test

Extra: The methemoglobin reduction test is another screening option. Heinz bodies (denatured hemoglobin) are visualized using supravital stains like crystal violet during an acute hemolytic episode. The definitive/confirmatory test is a quantitative G6PD enzyme assay.