Cell injury — Flashcards

Flashcard 171: Pathologic generation of free radicals arises with ionizing radiation, which hydrolyzes H2O to _____

Answer: Hydroxyl radical (OH\u2022)

Extra: Ionizing radiation causes the radiolysis (often referred to as hydrolysis in some review texts) of water, generating the hydroxyl radical (OH\u2022), which is the most damaging free radical produced in this process.

Flashcard 172: Cellular injury is characterized by _____ activity of the Na+-K+ and Ca2+ pumps

Answer: decreased

Flashcard 173: Are patients with metastatic calcifications usually normocalcemic? _____

Answer: No

Flashcard 174: Saponification of fat appears _____ (color) on H&E stain

Answer: dark blue

Flashcard 175: What RBC morphology is present in hemolytic uremic syndrome (HUS)?_____

Answer: Schistocytes (helmet cells)

Flashcard 176: Acute pancreatitis results in _____ necrosis of the pancreas

Answer: liquefactive

Flashcard 177: Heinz bodies form due to precipitation of denatured _____ within RBCs

Answer: globin chains

Flashcard 178: Which type of calcification (dystrophic or metastatic) occurs in abnormal, necrotic tissues? _____

Answer: Dystrophic

Flashcard 179: Atrophy via decrease in cell size may occur via _____ of cellular components

Answer: autophagy

Flashcard 180: What is the term for acute tubular necrosis (ATN) caused by toxic substances?

Answer: Nephrotoxic ATN