Cell injury — Flashcards

Flashcard 161: Which mechanism of cell death is an ATP-dependent programmed cell death? _____

Answer: Apoptosis

Flashcard 162: Hereditary spherocytosis demonstrates increased spherocyte fragility in _____-tonic solution (osmotic fragility test)

Answer: hypo

Flashcard 163: In G6PD deficiency, Heinz bodies are removed from RBCs by splenic macrophages, resulting in formation of _____ cells

Answer: bite

Flashcard 164: Which type of necrosis is associated with bacterial (ie: Klebsiella) lung abscesses?_____

Answer: Liquefactive

Flashcard 165: Which feature of cell death is characterized by nuclear dissolution? _____

Answer: Karyolysis

Flashcard 166: The targetoid appearance of erythema multiforme is due to central epidermal _____, surrounded by erythema

Answer: necrosis

Flashcard 167: Which mechanism of cell death involves death of single cells or small groups of cells? _____

Answer: Apoptosis

Flashcard 168: _____ are a histological feature of HPV infected cells and involve a nucleus with a 'raisin-like' shape.

Answer: Koilocytes

Flashcard 169: Are patients with metastatic calcifications usually normocalcemic? _____

Answer: No

Flashcard 170: Pathologic generation of free radicals arises with ionizing radiation, which hydrolyzes H2O to _____

Answer: Hydroxyl radical (OH\u2022)

Extra: Ionizing radiation causes the radiolysis (often referred to as hydrolysis in some review texts) of water, generating the hydroxyl radical (OH\u2022), which is the most damaging free radical produced in this process.