Liver disease — Flashcards

Flashcard 421: Does anemia persist following splenectomy in a patient with hereditary spherocytosis? _____

Answer: No

Flashcard 422: Cirrhosis may present with _____ due to decreased synthesis of clotting factors

Answer: coagulopathies

Flashcard 423: Does cirrhosis result in unconjugated or conjugated hyperbilirubinemia? _____

Answer: Both

Flashcard 424: Osmotic Demyelination Syndrome is also referred to as _____

Answer: Central pontine myelinolysis

Flashcard 425: Hemochromatosis is characterized by _____ TIBC

Answer: decreased

Flashcard 426: Carcinoid syndrome may occur if the carcinoid tumor metastasizes to the _____

Answer: liver

Flashcard 427: PiMZ heterozygotes (Alpha-1 antitrypsin) are at significant risk for emphysema if they _____

Answer: smoke

Flashcard 428: Lamivudine and tenofovir are NRTIs with activity against _____ (liver pathology)

Answer: hepatitis B

Flashcard 429: What demographic is associated with Coxiella burnetii pneumonia? _____

Answer: Farmers and veterinarians

Flashcard 430: Chronic exposure to _____ can occur with patients who work with metallurgy, dye and pigment manufacturing, wood preservatives

Answer: Arsenic

Extra: Arsenic exposure is a risk factor for **angiosarcoma of the liver**. Other high-yield associations include: - **Industries:** Metallurgy (smelting), wood preservatives (chromated copper arsenate), pesticides, and pigments. - **Malignancies:** Lung cancer, squamous cell carcinoma (skin), and hepatic angiosarcoma. - **Physical findings:** Palm/sole hyperkeratosis, hyperpigmentation, and Mees' lines (fingernails).