Drug-induced liver injury US Medical PG Flashcards - Medical Study Cards
Master Drug-induced liver injury with OnCourse flashcards. These spaced repetition flashcards are designed for medical students preparing for NEET PG, USMLE Step 1, USMLE Step 2, MBBS exams, and other medical licensing examinations.
Drug-induced liver injury Flashcard Deck - 10 Cards
Flashcard 1: Hepatic encephalopathy may be triggered by decreased NH3 removal, such as _____ failure
Answer: renal
Flashcard 2: Which infectious liver mass is typically treated pharmacologically without the need for routine drainage?
Answer: Amoebic liver abscess (Entamoeba histolytica)
Extra: Amoebic liver abscesses are typically managed with pharmacological therapy (Metronidazole followed by a luminal amebicide like paromomycin) and rarely require drainage. This contrasts with pyogenic liver abscesses, which usually require both drainage and antibiotics.
Flashcard 3: Viral hepatitis is characterized by elevated liver enzymes with ALT _____ AST
Answer: >
Flashcard 4: Alcoholic hepatitis may present with _____ hepatomegaly (painful or painless)
Answer: painful
Flashcard 5: Which liver lesion presents as a mass that is primarily treated pharmacologically (without routine drainage)?
Answer: Amoebic liver abscess (Entamoeba histolytica)
Extra: Amoebic liver abscesses are primarily treated with metronidazole followed by a luminal amebicide (e.g., paromomycin). Unlike pyogenic abscesses (which require drainage) or hydatid cysts (which often require PAIR or surgery), amoebic abscesses usually respond to medical therapy alone.
Flashcard 6: What is the triad of Meigs' syndrome?
Answer: Ovarian fibroma, ascites, and pleural effusion (hydrothorax)
Extra: Characteristics: The triad resolves after removal of the tumor. The pleural effusion is typically right-sided.
Note: Pseudo-Meigs syndrome involves ascites and pleural effusion associated with other pelvic/ovarian tumors (e.g., leiomyoma, mucinous cystadenoma) rather than a fibroma.
Flashcard 7: What conditions are associated with myoclonus?
Answer: metabolic abnormalities e.g. renal or liver failure
Flashcard 8: hepatic encephalopathy (ammonia intoxication)
Answer: acquired (liver failure) or hereditary (enzyme deficiency)
Extra: excess NH4+ in blood and inhibition of TCA cycle asterixis, slurred speech, blurred vision, somnolence, vomiting, cerebral edema limit protein in diet, benzoate or phenylbutyrate, lactulose
Flashcard 9: _____ presents as a mass in the liver that is treated pharmacologically
Answer: Entamoeba histolytica
Extra:
Watch Entamoeba histolytica [https://dashboard.sketchy.com/study/medical/courses/medical-microbiology/units/medical-microbiology-parasites/videos/medical-microbiology-parasites-protozoa-of-the-intestinal-tract-entamoeba-histolytica?utm_source=anki&utm_medium=partnership&utm_campaign=february_update&utm_content=medical]
https://onlinemeded.org/spa/microbiology/protozoa/acquire?ref=anki
Flashcard 10: Hepatitis A infection symptoms typically last _____
Answer: 1 month
Extra:
Watch Hepatitis A virus (PicoRNAviridae) [https://dashboard.sketchy.com/study/medical/courses/medical-microbiology/units/medical-microbiology-viruses/videos/medical-microbiology-viruses-rna-viruses-positive-sense-hepatitis-a-virus-picornaviridae?utm_source=anki&utm_medium=partnership&utm_campaign=february_update&utm_content=medical] Watch associated Bootcamp video [https://app.bootcamp.com/med-school/gastroenterology/videos/hepatic-pathology?index=4]
https://onlinemeded.org/spa/gastroenterology/viral-hepatitis/acquire?ref=anki
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