Molecular Genetics — Flashcards

Flashcard 741: Which enzyme is responsible for elongating the DNA strand? _____

Answer: DNA polymerase (specifically, DNA polymerase III in prokaryotes)

Flashcard 742: What is the inheritance of familial hypocalciuric hypercalcemia (FHH)? _____

Answer: Autosomal dominant

Flashcard 743: If a male has an X-linked recessive disease, all of his daughters will be _____

Answer: carriers

Flashcard 744: Mutation in the sonic hedgehog gene can cause _____

Answer: holoprosencephaly (specific/head)

Flashcard 745: Hemoglobin C disease is caused by a mutation in the _____ chain of hemoglobin

Answer: Beta (β) globin

Extra: Hemoglobin C (HbC) is caused by a missense mutation in the **β-globin** gene, resulting in the substitution of **glutamic acid** with **lysine** at position 6 (Glu6Lys). Mnemonic: Ly**C**ine for Hb**C**; **V**al**S**ine for Hb**S**.

Flashcard 746: What is another name for prokaryotic topoisomerase II? _____

Answer: DNA gyrase

Flashcard 747: Cyclin D1 sits on chromosome _____

Answer: 11

Flashcard 748: What form of chromatin is less condensed? _____

Answer: Euchromatin

Flashcard 749: The closer the recombination frequency is to _____%, the closer alleles in a haplotype are to each other

Answer: 0

Flashcard 750: What type of primer is used in a polymerase chain reaction (PCR)?_____

Answer: DNA primer