Molecular Genetics — Flashcards

Which replication enzyme is a RNA-dependent DNA polymerase, and thus a major example of reverse transcriptase activity, in humans? _____

The 5 to 3' exonuclease activity of prokaryotic DNA polymerase I is to remove the _____

Administration of hydroxyurea can lead to a build-up of _____ or CTP in the cell

A mutation in Rb results in constitutively free _____, leading to uncontrolled cell cycle progression

Which type of antibody digestion results in 2 monovalent Fab regions and 1 Fc region? _____

What sequence of nucleotides is repeated in Huntington disease?_____

Zellweger syndrome is a result of mutations in _____ genes that encode for peroxins, which are required for normal assembly of peroxisomes

Mutations in PTEN lead to overactivity of _____ proto-oncogene

_____ is the highest order of packaging of the chromosome

A _____ system can inducibly manipulate genes at specific developmental points (e.g. study a gene whose deletion causes embryonic deaths)