Molecular Genetics — Flashcards

What is the mode of inheritance of medium chain acyl-CoA dehydrogenase (MCAD) deficiency? _____

The 5 to 3' exonuclease activity of prokaryotic DNA polymerase I is to remove the _____

_____ is a lysosomal storage disease caused by frameshift mutations.

Autosomal dominant diseases are often due to defects in _____ genes

How many primers are needed for polymerase chain reaction (PCR)? _____

A mutation in Rb results in constitutively free _____, leading to uncontrolled cell cycle progression

Is mitochondrial DNA circular or linear?_____

Which type of antibody digestion results in 2 monovalent Fab regions and 1 Fc region? _____

Which replication enzyme is a RNA-dependent DNA polymerase, and thus a major example of reverse transcriptase activity, in humans? _____

Administration of hydroxyurea can lead to a build-up of _____ or CTP in the cell