Molecular Genetics — Flashcards

Topoisomerase _____ induces breaks in both the positive and negative DNA strands (double stranded breaks)

What form of chromatin is transcriptionally inactive and sterically inaccessible? _____

Does reverse transcriptase require a primer?_____

The APC tumor suppresor regulates the Wnt signalling pathway by destroying _____ in the absence of a Wnt receptor-ligand interaction

What type of oncogene is ABL?_____

A _____ transgenic mouse has had a gene inserted

Apoptosis is mediated by _____, which activate proteases and endonucleases

A _____ is detected with FISH as an extra site of fluorescence on one chromosome relative to its homologous chromosome

Which cell cycle checkpoint is blocked by hypophosphorylated Rb?_____

One feature of the genetic code is that it is _____: most amino acids are coded by multiple codons