Molecular Genetics — Flashcards

Topoisomerase _____ induces breaks in both the positive and negative DNA strands (double stranded breaks)

Which cell cycle checkpoint is blocked by hypophosphorylated Rb?_____

The _____ is a Y-shaped region along the DNA template where leading and lagging strands are synthesized

What type of oncogene is ABL?_____

One feature of the genetic code is that it is _____: most amino acids are coded by multiple codons

Does reverse transcriptase require a primer?_____

The APC tumor suppresor regulates the Wnt signalling pathway by destroying _____ in the absence of a Wnt receptor-ligand interaction

A _____ is a base plus a sugar (ribose or deoxyribose)

A _____ is detected with FISH as an extra site of fluorescence on one chromosome relative to its homologous chromosome

_____ have membrane bound organelles and nuclei