Molecular Genetics — Flashcards

What DNA-binding motif is common to cAMP response element binding (CREB) proteins? _____

Which cell cycle checkpoint is blocked by hypophosphorylated Rb?_____

mTOR is a _____

A _____ is a base plus a sugar (ribose or deoxyribose)

The _____ is a Y-shaped region along the DNA template where leading and lagging strands are synthesized

Sickle cell trait results in _____ 50% HbS in RBCs

What is the mode of inheritance of Fabry disease?_____

Topoisomerase _____ induces breaks in both the positive and negative DNA strands (double stranded breaks)

A _____ transgenic mouse has had a gene inserted

A _____ is detected with FISH as an extra site of fluorescence on one chromosome relative to its homologous chromosome