Molecular Genetics — Flashcards

Patients with kallmann syndrome most commonly have mutations in the _____ or FGFR-1 genes

If two linked genes have a recombination frequency of 15%, approximately how far apart are they?_____

One feature of the genetic code is that it is _____: each codon specifies only 1 amino acid

What class of enzymes cleaves nucleotides in the middle of a DNA strand? _____

What tumour suppressor gene does the E6 protein from Human Papillomavirus (HPV) bind to and inhibit?_____

Upregulation of _____ prevents chromosomal shortening and cell death in tumors

What type of probe is used to bind DNA/RNA when using a Southern/Northern blot? _____

Which hemoglobin type migrates the least far from the negative electrode on electrophoresis? _____

A _____ mutation occurs when a nucleotide substitution codes for a stop codon

What is the mode of inheritance of Tay-Sachs disease?_____