Molecular Genetics — Flashcards

Which tumor suppressor genes are associated with colon cancer?_____

What is the most common mode of inheritance of Alport syndrome? _____

If two linked genes have a recombination frequency of 15%, approximately how far apart are they?_____

What class of enzymes cleaves nucleotides in the middle of a DNA strand? _____

What type of probe is used to bind DNA/RNA when using a Southern/Northern blot? _____

Upregulation of _____ prevents chromosomal shortening and cell death in tumors

A _____ mutation occurs when a nucleotide substitution codes for a stop codon

A _____ is made up of a strand of DNA wrapped nearly twice around two copies of H2A, H2B, H3, and H4

In both Angelman syndrome and Prader-Willi syndrome, the most common abnormality is a gene _____

Which purine is characterized by no amino group at the 12 o'clock position?_____