Molecular Genetics — Flashcards

What class of enzymes cleaves nucleotides in the middle of a DNA strand? _____

A(n) _____ is negatively charged DNA wrapped around the outside of positively charged proteins called histones

Hemochromatosis may be primary; due to _____ mutations in iron absorption

Hint: inheritance pattern

A(n) _____ blot is used to identify DNA-binding proteins using labeled oligonucleotide probes

Hereditary spherocytosis most commonly involves defects in _____, spectrin, Band 3, or protein 4.2

A mutation at a(n) _____ results in a retained intron in the mRNA, leading to a protein with impaired or altered function

Hemoglobin C disease is caused by a mutation in the _____ chain of hemoglobin

Which replication enzyme is a RNA-dependent DNA polymerase, and thus a major example of reverse transcriptase activity, in humans? _____

What is the effect of increased G-C content on the melting temperature of a DNA strand? _____

Mitochondrial diseases often demonstrate variable expression in a population or within a family due to _____