Metabolism — Flashcards

What part of the cell is the site of steroid synthesis and detoxification of drugs and poisons?_____

What does the carrier molecule thiamine pyrophosphate (TPP) carry in its activated form? _____

Does heme synthesis occur in the cytoplasm or mitochondria? _____

Ketogenesis occurs in alcoholism due to excess _____, which causes shunting of oxaloacetate to malate

Is the conversion of glucose-6-P into ribulose-5-P (HMP shunt) a reversible or irreversible reaction? _____

Do irreversible competitive inhibitors bind to the active site of the enzyme?_____

Increased phenylalanine (e.g. in PKU) results in excess _____ in the urine

Which intercept of a Lineweaver-Burk plot represents -1/Km?

A _____ enzyme adds a hydroxyl group onto a substrate

Does activity of the HMP shunt produce ATP? _____